abstract：:Conventional treatment of acute and chronic renal diseases has focused on solute removal. Novel strategies aim to treat the multifactorial disease states of acute kidney injury and chronic kidney disease by mitigating inflammation. Cell-based technologies for the treatment of kidney dysfunction fall under two broad ca...

journal_title：Blood purification

authors： Pino CJ,Yevzlin AS,Tumlin J,Humes HD

更新日期：2012-01-01 00:00:00

abstract：:Dialysis dependence at hospital discharge after acute kidney injury (AKI) requiring renal replacement therapy (RRT) in the intensive care unit (ICU) is found in 10-15% of survivors. In case of severe AKI in the ICU, it is necessary to reconcile two objectives: the creation of an adequate temporary angioaccess for RRT ...

journal_title：Blood purification

authors： Wilson P,Lertdumrongluk P,Leray-Moragués H,Chenine-Koualef L,Patrier L,Canaud B

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Citrate anticoagulation offers several advantages in comparison to conventional anticoagulation. Most algorithms for regional citrate-calcium anticoagulation are based on citrate and calcium chloride infusion coupled in a fixed proportion to the blood flow without considering the hematocrit (Hct)/plasma flow...

journal_title：Blood purification

authors： Brandl M,Strobl K,Hartmann J,Kellner K,Posnicek T,Falkenhagen D

更新日期：2012-01-01 00:00:00

abstract：AIMS:To improve the side effects caused by sodium citrate (Na(3)Cit), the anticoagulant effects of diethyl citrate (Et(2)Cit) were investigated. METHODS:The in vitro anticoagulant effects and dissociation capacity of the chelate of Et(2)Cit with calcium ions were compared with those of Na(3)Cit in rabbits. RESULTS:Th...

journal_title：Blood purification

authors： Chen Z,Chen B,Yao XQ,Gui BS,Ou Y,Ouyang JM

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:We proposed a new method to estimate dry weight (DW) using single frequency bioimpedance. METHODS:We hypothesized that the change in whole body resistance at 50 kHz (R(50)) was proportional to the ultrafiltration volume (UFV) during a hemodialysis (HD) session. When the targeted resistance estimated in heal...

journal_title：Blood purification

authors： Dou Y,Cheng X,Liu L,Bai X,Wu L,Guo W,Zhao X,Wang F,Cao L,Zuo L

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Satisfactory and noninvasive diagnostic tools for coronary artery disease (CAD) are not available in hemodialysis patients. We aimed to elucidate a reliable tool to diagnose CAD in these patients. METHODS:102 hemodialysis patients received 2D speckle-tracking echocardiography with left ventricular (LV) stra...

journal_title：Blood purification

authors： Liu YW,Su CT,Wang SP,Yang CS,Huang JW,Hung KY,Chen JH,Tsai WC

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:We studied the influence of acute renal failure (ARF) on the relationship between N-terminal pro-B-type natriuretic peptide (NT-proBNP) and hemodynamic parameters. METHODS:The echocardiographic parameters and NT-proBNP levels were compared between 26 mechanically ventilated patients with ARF requiring conti...

journal_title：Blood purification

authors： Balik M,Jabor A,Otahal M,Waldauf P,Pavlisova M

更新日期：2011-01-01 00:00:00

abstract：:A significant and increasing number of chronic kidney disease (CKD) patients are treated with online hemodiafiltration (OL-HDF), even in the absence of more conclusive survival data. OL-HDF affords several clinical benefits including control of anemia of CKD, a common affliction in dialysis patients. In efforts to und...

journal_title：Blood purification

authors： Bowry SK,Gatti E

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:We estimated the flow of endotoxins (ET) from dialysates into the blood of patients on hemodialysis (HD) using limulus amebocyte lysate (LAL) assays and endotoxin activity (EA) determined by neutrophil respiratory burst activity. METHODS:A cross-sectional study compared groups given ultrapure bicarbonate (n...

journal_title：Blood purification

authors： Suzuki H,Honda H,Kato N,Michihata T,Takahashi K,Shishido K,Akizawa T

更新日期：2011-01-01 00:00:00

abstract：:The recent interest in the role of the intestine in the cardiovascular stability of uremic patients, specifically on dialysis, but potentially also in chronic kidney disease, must be seen against the background of the recent great interest in the role of the gut in chronic heart failure [Curr Opin Clin Nutr Metab Care...

journal_title：Blood purification

authors： Ritz E

更新日期：2011-01-01 00:00:00

abstract：:Chronic kidney disease (CKD) is associated with multiple detrimental consequences to the cardiovascular and musculoskeletal systems. The effects of CKD are even more significant when they begin in childhood as they affect growth and (neuro-) development as well. The division into stages of CKD serves as a guideline fo...

journal_title：Blood purification

authors： Goilav B,Kaskel FJ

更新日期：2011-01-01 00:00:00

abstract：:Despite advancements in dialysis therapy, the subjective clinical examination still remains the standard of care in managing volume removal in chronic dialysis. While there is no definitive trial establishing that dry weight management guided by an assistive technology is superior to the clinical method, there is ampl...

journal_title：Blood purification

authors： Sinha AD

更新日期：2011-01-01 00:00:00

abstract：:In this work we investigated the acute effects of hemodiafiltration with endogenous reinfusion (HFR therapy) on the removal of free immunoglobulin light chains (FIgLCs), which may be considered members of the family of uremic toxins. In two groups of patients - group 1 (polyclonal FIgLCs production) and group 2 (monoc...

journal_title：Blood purification

authors： Testa A,Dejoie T,Lecarrer D,Wratten M,Sereni L,Renaux JL

更新日期：2010-01-01 00:00:00

abstract：:Fluid overload may occur in critically ill patients as a result of aggressive resuscitation therapies. In such circumstances, persistent fluid overload must be avoided since it does not benefit the patient while it may be harmful. In the septic patient, early volume expansion seems to be beneficial. Beyond that thresh...

journal_title：Blood purification

authors： Cerda J,Sheinfeld G,Ronco C

更新日期：2010-01-01 00:00:00

abstract：:During hemodialysis, amino acids (AA) are lost in the ultrafiltrate with consequent modification of their plasma profile. The aim of this cross-sectional study was to evaluate intradialytic changes of plasma AA levels during a single session of hemodiafiltration with endogenous reinfusion (HFR) versus acetate-free bio...

journal_title：Blood purification

authors： Borrelli S,Minutolo R,De Nicola L,Zamboli P,Iodice C,De Paola A,De Simone E,Zito B,Guastaferro P,Nigro F,Apperti V,Iulianiello G,Credendino O,Iacono G,Di Serafino A,D'Apice L,Saviano C,Sarti A,Capuano M,Genualdo R,

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Psychological depression and physical disability are closely correlated in hemodialysis patients. A retrospective cohort study was conducted to examine the independent association of physical and psychological functioning with mortality in a hemodialysis cohort in Taiwan. METHODS:A total of 888 stable hemod...

journal_title：Blood purification

authors： Peng YS,Chiang CK,Hung KY,Chang CH,Lin CY,Yang CS,Chen TW,Hsia CC,Chen DL,Hsu WD,Chang CF,Wu KD,Lin RP,Tsai TJ,Chen WY

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Of 5 clinical trials testing dose response of continuous renal replacement therapy (CRRT) in acute kidney injury, 2 showed a benefit, 2 showed none, and 1 appeared equivocal. However, blood-membrane interactions may dominate macromolecule transport in continuous venovenous hemodiafiltration, reducing the imp...

journal_title：Blood purification

authors： Hofmann CL,Fissell WH

更新日期：2010-01-01 00:00:00

abstract：:Hypertension is present in most patients with end-stage renal disease and likely contributes to the premature cardiovascular disease in dialysis patients. Previous practice guidelines have recommended that, in patients on chronic dialysis, blood pressure (BP) should be reduced below 130/80 mm Hg. This is based on opin...

journal_title：Blood purification

authors： Redon J,Martinez F,Cheung AK

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:Peritonitis remains a significant problem for patients on peritoneal dialysis (PD). There is a certain amount of controversy as to whether peritoneal modality is itself a risk factor for peritonitis, with one modality higher than another. METHODS:A literature review was done (August 2009) searching und...

journal_title：Blood purification

authors： Piraino B,Sheth H

更新日期：2010-01-01 00:00:00

abstract：:While recent developments have allowed greater insight into the vascular pathobiology and intimal hyperplasia, very few of these advances have led to improved clinical care of hemodialysis vascular accesses. Indeed the most common procedure for the treatment of access stenosis and thrombosis is the same model for the ...

journal_title：Blood purification

authors： Diskin CJ

更新日期：2010-01-01 00:00:00

abstract：:Heart failure results in significant morbidity and mortality in the United States. Chronic heart failure is often complicated by renal insufficiency. Further, acute decompensated heart failure is often complicated by worsening renal function or the development of diuretic resistance. Heart failure complicated by renal...

journal_title：Blood purification

authors： Kociol R,Rogers J,Shaw A

更新日期：2009-01-01 00:00:00

abstract：:Effective dialysis therapy is now understood to encompass both small and large solute removal, using approaches that minimize intradialytic symptoms and maximize patient safety. Achieving the goal of providing effective dialysis for an expanding population of patients with increasingly complex medical problems at a ti...

journal_title：Blood purification

authors： Ward RA,Ronco C

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:To test the safety and efficacy of the Aethlon Hemopurifier, a lectin affinity cartridge, in clearing hepatitis C virus (HCV) from the blood of HCV-positive end-stage renal disease patients undergoing dialysis. Viral RNA was measured using real-time quantitative reverse transcriptase polymerase chain re...

journal_title：Blood purification

authors： Tullis RH,Duffin RP,Handley HH,Sodhi P,Menon J,Joyce JA,Kher V

更新日期：2009-01-01 00:00:00

abstract：:Chronic kidney disease-mineral and bone disorder is a new term defining a complex syndrome which underlines the need of a systemic approach to disturbances of calcium and phosphate metabolism in patients with renal failure. In recent years, the availability of new phosphorus binders and the appearance of new selective...

journal_title：Blood purification

authors： Bover J,Andrés E,Lloret MJ,Aguilar A,Ballarín J

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND AIM:Acute kidney injury (AKI) is a common complication in intensive care units (ICUs). However, its incidence and outcome vary in several studies depending on definitions used or even the geographic origin of the study. We aimed to evaluate the epidemiology of AKI in ICUs in Greece. METHOD:Prospective m...

journal_title：Blood purification

authors： Andrikos E,Tseke P,Balafa O,Cruz DN,Tsinta A,Androulaki M,Pappas M,Ronco C

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Diffuse hyperpigmentation is common in patients with chronic renal failure undergoing hemodialysis (HD) or peritoneal dialysis (PD). We previously reported that serum levels of 5-S-cysteinyldopa (5SCD, a pheomelanin precursor) and pheomelanin were significantly elevated in HD patients. METHODS:Skin color wa...

journal_title：Blood purification

authors： Murakami K,Nakanishi Y,Wakamatsu K,Yamamoto K,Kohriyama N,Hasegawa M,Tomita M,Nabeshima K,Hiki Y,Asano S,Kawashima S,Ito Y,Fujita Y,Asada H,Nakai S,Sugiyama S,Ito S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Wilson's disease (WD) can present in a fulminant form with hepatocellular dysfunction, hemolysis and multiorgan failure (Wilson's crisis). We present a previously healthy young woman with severe WD whose WD severity score was 13. A score >11 indicates a poor chance of survival and liver transplantation will ...

journal_title：Blood purification

authors： Aagaard NK,Thomsen KL,Holland-Fischer P,Jørgensen SP,Ott P

更新日期：2009-01-01 00:00:00

abstract：:In the last years, publications have questioned the classical dose of 35 ml/kg, but are those studies strong enough in terms of scientific power in order to change our practice? We will try to settle some recommendations for clinicians. Manipulation of dose, porosity, and combinations have yielded promising findings. ...

journal_title：Blood purification

authors： Honoré PM,Joannes-Boyau O,Collin V,Boer W,Jennes S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:In this study, we focused on whether volume overload plays a role in the development of arterial stiffness. METHODS:Seventy-three prevalent hemodialysis patients were enrolled in a cross-sectional study. Arterial stiffness was assessed by carotid-femoral pulse wave velocity (PWV), and volume overload was as...

journal_title：Blood purification

authors： Zheng D,Cheng LT,Zhuang Z,Gu Y,Tang LJ,Wang T

更新日期：2009-01-01 00:00:00

abstract：:The central dialysis fluid delivery system (CDDS) has been working exclusively in Japan since 1970, a fact which proves that CDDS is useful in the multi-patient treatment with in-center regular hemodialysis. It is a cost-effective, labor-saving and time-tested system with 40 years of experience. Microbial safety is im...

journal_title：Blood purification

authors： Koda Y,Mineshima M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Optimization of vascular access use in the 'fistula first' era requires comprehension of its clinical behavior. Little is known about mature arteriovenous fistula (AVF) performance and the role of fistula location. Widely used access flow (Qa) was used to analyze complication risks and functionality aft...

journal_title：Blood purification

authors： Huijbregts HJ,Bots ML,Wittens CH,Schrama YC,Blankestijn PJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Intravenous iron infusion is the accepted way of supplementation of that compound in uremic patients. The aim of the study was to evaluate whether this treatment affects intraperitoneal homeostasis in patients on peritoneal dialysis. METHODS:Blood and peritoneal dialysate samples were collected from 10...

journal_title：Blood purification

authors： Breborowicz A,Połubinska A,Kupczyk M,Wanic-Kossowka M,Oreopoulos DG

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Critically ill patients with acute kidney injury (AKI) are at high risk for death and frequently require initiation of renal replacement therapy (RRT). There is wide variation in clinical practice on the indications for and timing of initiation and discontinuation of RRT. Numerous clinical and biochemical fa...

journal_title：Blood purification

authors： Gibney RT,Bagshaw SM,Kutsogiannis DJ,Johnston C

更新日期：2008-01-01 00:00:00

abstract：:Heart failure (HF) is a chronic disease process associated with significant morbidity and mortality. Hospitalizations for acute decompensation may be frequent and herald a downward trajectory for the underlying disease state and overall poor prognosis for the patient. While significant advances have been made in the r...

journal_title：Blood purification

authors： Virani SA

更新日期：2008-01-01 00:00:00

abstract：:Guidelines have been developed in nephrology and medicine developed to assist practitioners and patients in making decisions about healthcare for specific clinical circumstances. There has been a proliferation of guidelines over the last decade in all areas of medicine, including nephrology. Many of the nephrology gui...

journal_title：Blood purification

authors： Levin A

更新日期：2008-01-01 00:00:00

abstract：AIMS:To assess whether kidney transplantation improves sleep-related breathing disorders associated with hemodialysis. METHODS:A prospective study was carried out using full-night polysomnography. Nine hemodialysis patients (7 men and 2 women, aged 42 +/- 16.2 years, BMI 26 +/- 3.7) who later received a successful kid...

journal_title：Blood purification

authors： Jurado-Gámez B,Martin-Malo A,Rodriguez-Benot A,Muñoz-Cabrera L,Cosano Povedano A,Aljama P

更新日期：2008-01-01 00:00:00

abstract：:Long-term dialysis in children with multiple handicaps has become easier with the advent of continuous ambulatory peritoneal dialysis (PD). Due to the widespread use of PD and the long survival of patients with spina bifida, an increasing number of patients with spina bifida are on PD. The viability and safety of PD i...

journal_title：Blood purification

authors： Ram Prabahar M,Sivakumar M,Chandrasekaran V,Indhumathi E,Soundararajan P

更新日期：2008-01-01 00:00:00

abstract：:In patients with chronic kidney disease (CKD), peptides and proteins circulate at altered concentrations versus in healthy individuals. We have characterized proteome samples from 7 pooled CKD stage 5 patients not yet on dialysis and with no known co-morbidities. We also analyzed pooled plasma samples from 7 healthy a...

journal_title：Blood purification

authors： Naseeb U,Shafqat J,Jägerbrink T,Zarina S,Alvestrand A,Jörnvall H,Axelsson J

更新日期：2008-01-01 00:00:00

abstract：:Medicare pays 80% of the cost of dialysis treatment and associated medications. Congress directed the Centers for Medicare and Medicaid Services (CMS) to develop both a process of regular and more or less "automatic" updates of composite rate setting and "bundling" as much of the laboratory and ancillary medications a...

journal_title：Blood purification

authors： DeOreo PB

更新日期：2007-01-01 00:00:00

abstract：:Dialysis fluid is produced by the blending of treated water with electrolytes at the patients bed side. Its preparation and composition are important elements of treatment optimisation since many of the constituents play a role in patient well-being. Ideally the composition of the dialysis fluid should match that of p...

journal_title：Blood purification

authors： Hoenich NA,Ronco C

更新日期：2007-01-01 00:00:00